What is Modecate drug used for?

What is Modecate drug used for?

Fluphenazine is a phenothiazine, also called a neuroleptic, used to treat symptoms of a certain type of mental/mood condition (schizophrenia). Fluphenazine is available under the following different brand names: Modecate, Modecate Concentrate, Moditen, Prolixin (discontinued brand), and RhoFluphenazine.

Why is Modecate being discontinued?

BMS have notified the end of production of Modecate Injection due to the unpredictability of supply of fluphenazine decanoate, the active pharmaceutical ingredient (API), from the third party manufacturer, Fine Chemicals of South Africa. There are no other manufacturers of API worldwide.

How is Modecate given?

Modecate Concentrate is normally given by a doctor or nurse. This is because it needs to be given as a deep injection into a muscle. If you are not sure why you are being given Modecate Concentrate or have any questions about how much Modecate Concentrate is being given to you, speak to your doctor or nurse.

Is Modecate still available?

Fluphenazine decanoate 25mg/1ml and 100mg/1ml solutions for injection ampoules (Modecate and Modecate Concentrate) manufactured by Sanofi, have been discontinued for some time and stock of any remaining batches will now have expired.

How long does Modecate take to work?

12.5mg (0.0625ml ie 6.25mg for patients over 60) by deep intramuscular injection into the gluteal region. The onset of action generally appears between 24 and 72 hours after injection and the effects of the drug on psychotic symptoms become significant within 48 to 96 hours.

How long does Modecate last?

The injection slowly releases fluphenazine into your body and is given every 2-5 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day….About fluphenazine long-acting injection.

What is the other name for Modecate?

About fluphenazine long-acting injection

When was Modecate discontinued?

Discontinuation report MODECATE CONCENTRATE

Does prolixin cause depression?

Tell your doctor right away if you have any serious side effects, including: feelings of restlessness, mask-like facial expression, greatly increased saliva, tremors, unusual mental/mood changes (such as depression, worsening of psychosis), confusion, unusual dreams, frequent urination or difficulty urinating, vision …

How do you give a Modecate injection?

Your Modecate treatment will be given to you by a doctor or a nurse. In adults, treatment is usually started with a dose of 12.5 mg, given by deep intramuscular injection, usually into the buttock. Subsequent dosage is usually 25 mg every 2 to 4 weeks. This may be increased to 100 mg depending on your illness.

What is the other name for benzhexol?

Trihexyphenidyl, also known as benzhexol, trihex, Artane, or even THP is an antiparkinsonian agent of the antimuscarinic class. It was approved by the FDA for the treatment of Parkinson’s in 2003.

How effective is modecate injection?

While Modecate injection has been shown to be effective in acute states, it is particularly useful in the maintenance treatment of chronic patients who are unreliable at taking their oral medication, and also of those who do not absorb their oral phenothiazine adequately.

How much fluphenazine is in modmodecate?

Modecate Injection 25mg/ml 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Each ampoule contains 25mg/ml of the active substance Fluphenazine Decanoate.

Can modecate be used to treat dementia-related psychosis?

This drug is not approved for treatment of patients with dementia-related psychosis. This medication contains fluphenazine. Do not take Modecate, Modecate Concentrate, Moditen, Prolixin, or RhoFluphenazine if you are allergic to fluphenazine or any ingredients contained in this drug.