What is MITF gene?

What is MITF gene?

The MITF gene provides instructions for making a protein called melanocyte inducing transcription factor. This protein plays a role in the development, survival, and function of certain types of cells.

What happens to DNA when there is a mutation?

A mutation is a change in the DNA sequence of a gene. Though some mutations are harmful, most are not. A mutation may change a trait in a way that may even be helpful, such as enabling an organism to better adapt to its environment. The simplest mutation is a point mutation.

What is SOX10 gene?

Collapse Section. The SOX10 gene belongs to a family of genes that plays a critical role in the formation of tissues and organs during embryonic development. The SOX gene family also maintains the normal function of certain cells after birth.

Is SOX9 on the Y chromosome?

SOX9 is a transcription factor essential for both sex and skeletal development. Transient expression of the Y chromosome gene SRY (480000) initiates a cascade of gene interactions orchestrated by SOX9, leading to the formation of testes from bipotential gonads (summary by Cox et al., 2011).

What does Sox10 positive mean?

SOX10 (Sry-related HMg-Box gene 10) is a key nuclear transcription factor in the differentiation of neural crest progenitor cells to melanocytes. It has been shown to be a sensitive and specific marker of malignant melanoma of multiple histologic types.