What isvicinal diol?
vicinal diol(Noun) Any diol in which the two hydroxy functional groups are attached to adjacent carbon atoms.
How do you convert diols to lactones?
Diols can also be converted to lactones employing the Fétizon oxidation reaction. In glycol cleavage, the C−C bond in a vicinal diol is cleaved with formation of ketone or aldehyde functional groups. See Diol oxidation .
How are vicinal diols obtained from alkenes?
Because vicinal diols are obtained from alkenes, the combination of dihydroxylation followed by oxidative cleavage of a diol provides an alternative method to ozonolysis of alkenes to yield the same products. We can deduce the structure of the starting diol from the structures of the carbonyl compounds.
What are the different methods of Vic-diolation?
Another method is the Woodward cis-hydroxylation (cis diol) and the related Prévost reaction (anti diol), depicted below, which both use iodine and the silver salt of a carboxylic acid. Other routes to vic-diols are the hydrogenation of acyloins and the pinacol coupling reaction.
