What is emetogenic risk?

What is emetogenic risk?

GLOSSARY. Emetogenicity: the propensity of an agent to cause nausea, vomiting or retching. High emetic potential: greater than 90% frequency of emesis in the absence of effective prophylaxis.

What drug has emetogenic potential?

Table 2

What does highly emetogenic mean?

Listen to pronunciation. (eh-MEH-toh-JEH-nik) Describes a substance that causes vomiting. Also called emetic.

What chemo drugs are highly emetogenic?

Some highly emetogenic agents and chemotherapy regimens include:

• ABVD.
• AC.
• BEP.
• Cisplatin.
• Carmustine (>250 mg/m2)
• CBV.
• Cyclophosphamide (>1500 mg/m2)
• Dacarbazine.

Is carboplatin highly emetogenic?

The NCCN has recently reclassified carboplatin emetogenicity according to the AUC (target area under the concentration versus time curve) with a carboplatin AUC ≥4 classified as highly emetogenic and carboplatin AUC < 4 as moderately emetogenic – but highly emetogenic in certain patients.

Which chemotherapy agent has the lowest emetogenic potential?

Drugs considered to have low emetogenic risk (10%-30%) include the taxanes, etoposide, and biologics such as trastuzumab (Herceptin) and cetuximab (Erbitux). Some antineoplastic agents such as the vinca alkaloids as a class or bevacizumab (Avastin) are associated with minimal risk of emesis without prophylaxis (< 10%).

Which chemotherapy agent has the highest emetogenic potential?

Hint: You can sort the table by clicking on the boxes containing arrows at the top of each column.

Which of the following medications is considered to have low Emetogenicity?

Drugs considered to have low emetogenic risk (10%-30%) include the taxanes, etoposide, and biologics such as trastuzumab (Herceptin) and cetuximab (Erbitux).

What are the long term side effects of carboplatin?

Sensory loss, numbness and tingling, and difficulty in walking may last for at least as long as therapy is continued. These side effects may become progressively more severe with continued treatment, and your doctor may decide to decrease your dose.

What are the phases of chemotherapy?

Treatment can be divided into four phases: First phase — induction chemotherapy Second phase — consolidation chemotherapy Third phase — maintenance chemotherapy Fourth phase — central nervous system (CNS) prophylaxis

What are chemotherapy agents?

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body. Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body.