What is desmoid tumor?
Desmoid tumors are also known as aggressive fibromatosis or desmoid-type fibromatosis. A desmoid tumor can occur anywhere in the body since connective tissue is found everywhere in your body. Desmoid tumors are often found in the abdomen, as well as the shoulders, upper arms, and thighs.
How do desmoid tumors form?
Doctors know these tumors form when a connective tissue cell develops changes in its DNA. A cell’s DNA contains the instructions that tell a cell what to do. The changes tell the connective tissue cell to multiply rapidly, creating a mass of cells (tumor) that can invade and destroy healthy body tissue.
What does a desmoid tumor feel like?
Symptoms may include: Soreness or pain caused by the tumor pressing on nearby nerves, muscles, or blood vessels. Tingling or a feeling of “pins and needles,” when the tumor presses on local nerves or blood vessels. Limping or other difficulties moving the legs or feet.
WHO classification desmoid tumors?
Desmoid tumors grow slowly. Their aggressiveness is local with no potential for metastasis or dedifferentiation. In the last 2012 World Health Organization (WHO) classification of sarcomas, they are classified as tumors with intermediate malignancy potential.
Can a desmoid tumor be removed?
When possible, desmoid tumors will be surgically removed. The procedure will usually take between three and five hours. Recovery typically takes a month or less. However, there is a high rate of recurrence with surgery alone.
Are desmoid tumors genetic?
Most desmoid tumors are sporadic and are not inherited. Sporadic tumors result from gene mutations that occur during a person’s lifetime, called somatic mutations. A somatic mutation in one copy of the gene is sufficient to cause the disorder.
