What does tubal metaplasia mean?
Definition: Tubal metaplasia of the endometrium refers to the presence of large number of tubal-type ciliated cells in the endometrial mucosa. It is usually an incidental finding but is seen more commonly in association with endometrial hyperplasia. It may result in abnormal cells in a Pap smear.
Is Tubal metaplasia normal?
Tubal (or ciliated cell) metaplasia of the endometrium is a frequent finding in endometrial sampling specimens and is commonly associated with the follicular phase of the menstrual cycle and with anovulatory cycles.
What causes tubal metaplasia?
Tubal metaplasia occurs in setting of estrogen excess or postmenopausal. Squamous metaplasia frequently occurs in hyperplasia, neoplasia, CEMI. The endometrium looks very much like the epithelium of the fallopian tube. Cilia are present.
Is Tubal metaplasia precancerous?
It is generally known that endometrial tubal metaplasia is a benign disease. However studies propose endometrial tubal metaplasia to be a potential premalignant endometrial lesion and its association with endometrial hyperplasia and well-differentiated endometrioid carcinoma.
What is ciliated tubal metaplasia?
The term ciliated cell or tubal metaplasia describes the replacement of the endometrial glandular lining by significant numbers of ciliated cells with round, non-atypical nuclei, a delicate chromatin pattern, and eosinophilic cytoplasm.
What is the purpose of metaplasia?
Metaplasia is a process whereby one type of mature tissue is replaced by another type of mature tissue not indigenous to that organ or tissue. Metaplastic transformation likely represents a reactive or reparative response to some chronic injury or irritation.
What is ciliary metaplasia?
What comes first metaplasia or dysplasia?
Dysplasia is the presence of abnormal cells within your tissue or one of your organs. Metaplasia is the conversion of one type of cell to another. Any of your normal cells may become cancer cells. Before cancer cells form in your body’s tissues, they go through abnormal changes called hyperplasia and dysplasia.
What is metaplasia in endocervix?
Metaplasia is a reversible reprogramming of stem cells of the epithelium. Usually, squamous metaplasia is observed in the endocervix. However, less frequently, tubal metaplasia may develop, replacing nonciliated columnar cells by ciliated columnar cells, similar to fallopian tube epithelium.
Is squamous metaplasia common in the endocervical canal?
Usually, squamous metaplasia is observed in the endocervix. However, less frequently, tubal metaplasia may develop, replacing nonciliated columnar cells by ciliated columnar cells, similar to fallopian tube epithelium. Here we present a case of tubal metaplasia of the endocervical canal.
Is Tubal metaplasia associated with cervical intraepithelial neoplasia?
Similarly, no association of tubal metaplasia has been found with any phase of the menstrual cycle or low-grade cervical intraepithelial neoplasia (CIN). However, tubal metaplasia was found to be inversely related to high-grade CIN in glands, presumably due to the replacement of metaplastic cells by neoplastic cells. [3]
Can cytobrush detect tubal metaplasia of the cervix?
Tubal metaplasia should be identified as a unique benign identity and should not be confused with early endocervical glandular neoplasia of the cervix. Cytobrush technique for endocervical smears helps detect such uncommon metaplastic changes. Keywords: Ciliated columnar endocervical cells; cytobrush sampling; tubal metaplasia.
