How do you know if you have muscle damage from statins?
One of the most common complaints of people taking statins is muscle pain. You may feel this pain as a soreness, tiredness or weakness in your muscles. The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult.
How long does it take to recover from statin induced myositis?
The majority of muscle damage by statins is secondary to its direct toxic effects, possibly via coenzyme Q10 depletion causing mitochondrial dysfunction. The injury is dose dependent and reversible after withdrawing the drug, with most recovery of symptoms occurring within 2–3 months (3).
How long does statin induced myopathy last?
For most patients, myopathy symptoms induced by statin therapy resolve relatively quickly; however, the results of the PRIMO study showed that it may take up to 2 months for resolution of symptoms.
Can statin induced myositis be reversed?
There is limited evidence regarding the treatment of statin-associated myopathy. While myopathy caused by statins can be mild and can be reversed when the medication is discontinued, it may present as rhabdomyolysis or severe muscle damage.
What does statin myopathy feel like?
SAMS can vary in frequency and severity. The following are the three most common forms of statin-related muscle pain: Myalgia: This type of muscle pain usually feels like mild soreness in the shoulders, arms, hips or thighs. Myalgia also often comes with mild feelings of weakness.
Will statin myopathy go away?
Statin-associated myopathy or myalgia is a well-known side effect of lipid-lowering agents. Usually, after discontinuation of the drug, symptoms alleviate and patients may be re-challenged with another statin. However, in rare cases, symptoms of myalgia do not subside after statins are discontinued.
How do you test for statin myopathy?
If you begin to show symptoms of muscle myopathy after starting statin therapy, talk to your doctor or physician as soon as possible. A blood test is usually ordered to measure creatine kinase levels and rule out rhabdomyolysis. If rhabdomyolysis is the culprit, statin treatment will be stopped immediately.
How do you reverse statin induced myopathy?
Currently, the only effective treatment of statin-induced myopathy is the discontinuation of statin use in patients affected by muscle aches, pains and elevated CK levels.
