How do you administer Remodulin?
Remodulin is administered subcutaneously by continuous infusion, via a subcutaneous catheter, using an infusion pump designed for subcutaneous drug delivery.
How long does Remodulin last?
Simple. Prefilled Remodulin cassettes help ensure you receive your intended dose of medication without the burden of mixing and are delivered to you by your Specialty Pharmacy. You can easily connect the cassette to your pump—just prime, twist, and go. Each cassette can keep you going for up to 3 days (72 hours).
Is Remodulin refrigerated?
Diluted Remodulin has been shown to be stable at ambient temperature when stored for up to 14 days using high-pH glycine diluent at concentrations as low as 0.004 mg/mL (4,000 ng/mL).
What is a Remodulin pump?
A small, discreet, water-resistant pump with prefilled cassettes designed to simplify the delivery of Remodulin* Learn More. *The Remunity pump can tolerate immersion in water to depths of up to 8 feet for 30 minutes and 12 feet for up to 3 minutes.
Can Remodulin be given IV?
Remodulin is indicated for subcutaneous (SC) or intravenous (IV) use only as a continuous infusion. Remodulin is preferably infused subcutaneously, but can be administered by a central intravenous line if the subcutaneous route is not tolerated, because of severe site pain or reaction.
How do you mix Remodulin?
When premixing for storing, Remodulin should be mixed with a sterile high-pH glycine diluent. Remodulin cannot be stored for 14 days when mixed with Sterile Water for Injection or Sodium Chloride Injection (only 4 hours at room temperature or 24 hours refrigerated).
What happens if you stop Remodulin?
You should not reduce your dose or stop using Remodulin suddenly. Stopping suddenly may make your condition worse. To make sure there is no interruption in your treatment, you may need to have a back-up infusion pump, replacement batteries, and extra infusion sets.
How do you titrate Remodulin?
Titrate up in 1.25 ng/kg/min increments per week to achieve a dose that improves PAH symptoms while minimizing excessive pharmacologic effects of Remodulin (ie, headache, nausea, emesis, restlessness, anxiety, and infusion site pain or reaction). Titrate slowly in patients with hepatic or renal insufficiency.
Does Remodulin lower blood pressure?
Treprostinil (Remodulin) can cause your blood pressure to drop, because the medication widens your blood vessels. Let your provider know if you feel dizzy or lightheaded while taking the medication.
What is the half-life of Flolan?
Elimination. The in vitro half-life of epoprostenol in human blood at 37°C and pH 7.4 is approximately 6 minutes; therefore, the in vivo half-life of epoprostenol in humans is expected to be no greater than 6 minutes.
How long can you stay on Flolan?
Freshly prepared reconstituted solutions or reconstituted solutions that have been stored at 2°C to 8°C (36°F to 46°F) for no longer than 8 days can be administered up to: 72 hours at up to 25°C (77°F).
Does Remodulin make you tired?
a light-headed feeling, like you might pass out; or. worsening PAH symptoms (tiredness, pale skin, chest pain, trouble breathing).
